The life cycles of business models are decreasing.

Constant innovation in both technology and business models means that established players are always in danger of being outflanked by more nimble competitors.

The key to survival is to continue to innovate new business models through a process of 1) deep insights, 2) inception, 3) validation and 4) ramp-and-run.

Both start-ups and established companies can benefit from collaborating with partners who know how to innovate through the fast-prototyping, fast-iteration and fast-learning model that Silicon Valley firms use to win the future.
Meet the Expert

About Dave

  • 33 years as CEO, consultant, in R&D management
  • CEO of three startup technology companies
  • Partner and Global Innovation Practice Leader at McKinsey & Company
  • Closed seven financings, $250M in licensing deals, $500M in M&A deals and created three large joint ventures with Fortune 500 corporate partners.


Partner • Business Model Innovations, LLC
Sep, 2014 — Present
Managing Director • Technology Pathfinders
Jun, 2008 — Sep, 2014
    • Founder of a consulting and interim management services firm.
  • Clients include: Khosla /ventures; Kleiner Perkins; Versant Ventures; Thomas McNerney Partners.
  • Mascoma (2009-2010), Chief Business Officer, clean tech company converts cellulosic feedstocks into ethanol.
  • Kinestral (2911-2012), Acting CEO, electrochromic window startup venture.
President & CEO • Acumen Pharmaceuticals
2002 — 2008
  • Pre-clinical drug company focused on treating Alzheimer's disease.
  • Negotiated deal with Merck for an R&D collaboration that put two antibodies on an IND (investigational new drug) track.
President & CEO • Mendel Biotechnology
1999 — 2002
  • Clean tech company focused on cellulosic ethanol
Director • Monsanto
1996 — 1999
  • Director - Food, Feed and Fiber
  • Led Monsanto's application of biotechnology to differentiate commodities in the feed and grain processing industries.
  • Negotiated joint ventures with Danisco (Animal Nutrition LLC) and Cargil (Renessen)
  • Director - Global Oilseeds Team
Partner • McKinsey & Company
1989 — 1996
  • Led the Global Innovation Practice
  • Core team member of the Global Technology Management Practice
Manager • Procter & Gamble
1981 — 1988
  • Corporate Finance and Planning, Account Management Team with WalMart.
  • Product Development - led product development teams in fabric and skin care categories.


Massachusetts Institute of Technology
MS, Chemical Engineering, 1985

Academic Awards

CEIP Fund Award
Massachusetts Institute of Technology
BS, Chemical Engineering, 1981

Academic Awards

Teagle Foundation Scholar


  • Board of Directors, Acumen Pharmaceuticals
  • Board of Directors, Sequoia Pharmaceuticals
  • Board of Directors, Agrivida, a Kleiner Perkins investment
  • Board of Directors, Mendel Biotechnology
  • Board of Directors, Neurotech Industry Organization
  • Leadership Board, McGovern Institute for Brain Research
  • Advisory Board, Institute for the Study of Aging
  • Board of Advisors, Perfection Learning (text books)
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